Wednesday, 28 June 2017

Evaluation of a Real-Time Polymerase Chain Reaction for the Laboratory Diagnosis of Giardia intestinalis in Stool Samples from Schoolchildren from the Centre-Ouest and Plateau Central Regions of Burkina Faso.

Giardiasis is a zoonotic disease that affects at least 280 million people worldwide each year. It is one of the main causes of nonviral diarrhoea in industrialized countries and it is associated with additional digestive disorders in children and adults including abdominal pain, nausea. Giardiasis can develop into a chronic condition, anddisease can be aggravated in immunocompromised hosts. Infection with the causative intestinal protozoa Giardia intestinalis is commonly associated with unsafe drinking water, poor hygiene and sanitation, poverty and warm climate. Correspondingly, the prevalence of G. intestinalis is estimated at 2-7% in developed countries and up to 20-30% in low- and middle-income countries (LMICs). Owing to their common faecal-oral mode of transmission G. intestinalis is often found in coinfection with other intestinal protozoa.
journal of applied microbiology

Studies among school-aged children across Africa are scarce; however, those available reports a G. intestinalis prevalence’s of 16% in urban and 24% in rural areas of Morocco and 11.7% in a rural setting in southern Ethiopia. From Côte D'Ivoire a 17.3% and 13.9% prevalence was demonstrated in the Man area and the region of Agboville, respectively. G. intestinalis prevalence in school children in Burkina Faso is currently described by several smaller studies reporting on local numbers, while the national prevalence unknown. One such study, conducted in 2014, has shown G. intestinalis prevalence’s of 13.3%, 12.5% and 9.8% among children aged 6-15 years from three different schools of the Central region. Another setting revealed a prevalence of 43.7% in patients aged 5 months to 72 years suffering from gastroenteritis visiting the Saint Camille Hospital of Ouagadougou. A retrospective study of parasitological aetiology assessments of gastroenteritis patients from the same hospital showed an infection rate of 24.8%.(Read more)

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